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Anthracosis

MedGen UID:
8107
•Concept ID:
C0003165
•
Disease or Syndrome
Synonyms: Anthracoses; Black Lung; Black Lung Disease; Black Lung Diseases; Black Lungs; Coal Miner Lung; Coal Miner's Lung; Coal Miner's Lungs; Coal Miners Lung; Coal Worker Pneumoconiosis; Coal Worker's Pneumoconioses; Coal Worker's Pneumoconiosis; Coal Workers Pneumoconiosis; Coalworker Pneumoconiosis; Coalworker's Pneumoconioses; Coalworker's Pneumoconiosis; Coalworkers Pneumoconiosis; Lung, Black; Lungs, Black; Miner's Lung, Coal; Miner's Lungs, Coal; Pneumoconioses, Coal Worker's; Pneumoconioses, Coalworker's; Pneumoconiosis, Coal Worker; Pneumoconiosis, Coal Worker's; Pneumoconiosis, Coal Workers; Pneumoconiosis, Coalworker's
SNOMED CT: CWP - Coalworkers pneumoconiosis (29422001); Coal worker's lung (29422001); Coal workers' pneumoconiosis (29422001); Coal pneumoconiosis (29422001); Colliers' lung (29422001); Colliers' anthracosis (29422001); Miners' lung (29422001); Melanedema (29422001); Anthracosis (29422001); Black lung disease (29422001); Coal workers' lung (29422001); Miners' asthma (29422001); Lung melanosis (29422001); Pneumomelanosis (29422001); Coal miners' lung (29422001); Coal miners' pneumoconiosis (29422001)
 
HPO: HP:0033375
Monarch Initiative: MONDO:0006654

Definition

Anthracosis is the deposition of black carbon pigment. It is commonly seen in perihilar lymph nodes as well as within lung parenchyma. There can be prominent storiforming (i.e., spiral patterning) of histiocytes, to such an extent as to mimic a neoplastic lesion histologically. Anthracosis is a common finding in smokers and polluted city dwellers. [from HPO]

Professional guidelines

PubMed

Heterozygous Ins/Del genotype of the CASP8 rs3834129 polymorphism significantly decreases the risk of coal workers' pneumoconiosis in a Chinese Han population: a case-control study.
Hou ZF, Wang H, Ji SQ, Kang DM, Zhao H, Guo Y, Ma JF, Wang JZ, Ma X, Gao Y
Eur Rev Med Pharmacol Sci 2021 Dec;25(24):7726-7733. doi: 10.26355/eurrev_202112_27619. PMID: 34982434
Respiratory surveillance for coal mine dust and artificial stone exposed workers in Australia and New Zealand: A position statement from the Thoracic Society of Australia and New Zealand.
Perret JL, Miles S, Brims F, Newbigin K, Davidson M, Jersmann H, Edwards A, Zosky G, Frankel A, Johnson AR, Hoy R, Reid DW, Musk AW, Abramson MJ, Edwards B, Cohen R, Yates DH
Respirology 2020 Nov;25(11):1193-1202. Epub 2020 Oct 13 doi: 10.1111/resp.13952. PMID: 33051927Free PMC Article
ACR Appropriateness Criteria Review ACR Appropriateness Criteria® Occupational Lung Diseases.
Expert Panel on Thoracic Imaging, Bacchus L, Shah RD, Chung JH, Crabtree TP, Heitkamp DE, Iannettoni MD, Johnson GB, Jokerst C, McComb BL, Saleh AG, Steiner RM, Mohammed TL, Ravenel JG
J Thorac Imaging 2016 Jan;31(1):W1-3. doi: 10.1097/RTI.0000000000000194. PMID: 26656194

Recent clinical studies

Etiology

Altered lymphatic structure and function in pleural anthracosis: negative role in skip N2 metastasis.
Takeda A, Ueda K, Aoki M, Nagata T, Kamimura G, Umehara T, Tokunaga T, Tabata K, Tanimoto A, Sato M
Eur J Cardiothorac Surg 2022 Aug 3;62(3) doi: 10.1093/ejcts/ezac123. PMID: 35211750
Bronchial Anthracofibrosis and Tracheobronchomalacia.
Samareh-Fekri M, Hashemi Bajgani SM, Shafahi A, Shafiepour M, Yazdani R, Ahmadpour Baghdadabad MH
Arch Iran Med 2021 Jun 1;24(6):467-472. doi: 10.34172/aim.2021.67. PMID: 34488309
State-of-the-art nanopathological diagnostics.
Roncati L, Barbolini G
Ultrastruct Pathol 2017 Sep-Oct;41(5):309-311. Epub 2017 Aug 14 doi: 10.1080/01913123.2017.1358227. PMID: 28805487
Coal workers' pneumoconiosis: an Australian perspective.
Zosky GR, Hoy RF, Silverstone EJ, Brims FJ, Miles S, Johnson AR, Gibson PG, Yates DH
Med J Aust 2016 Jun 20;204(11):414-8. doi: 10.5694/mja16.00357. PMID: 27318401
Frequency of tuberculosis in anthracosis of the lung: a systematic review.
Mirsadraee M, Saffari A, Sarafraz Yazdi M, Meshkat M
Arch Iran Med 2013 Nov;16(11):661-4. PMID: 24206409

Diagnosis

Bronchial Anthracofibrosis and Tracheobronchomalacia.
Samareh-Fekri M, Hashemi Bajgani SM, Shafahi A, Shafiepour M, Yazdani R, Ahmadpour Baghdadabad MH
Arch Iran Med 2021 Jun 1;24(6):467-472. doi: 10.34172/aim.2021.67. PMID: 34488309
Scary black nodes.
Bharti JN, Soudamini AB, Kaushal D
Diagn Cytopathol 2021 Aug;49(8):E286-E290. Epub 2021 Feb 8 doi: 10.1002/dc.24711. PMID: 33555660
Dust to dust.
McGuire C
Lancet Respir Med 2019 May;7(5):383-384. Epub 2019 Apr 5 doi: 10.1016/S2213-2600(19)30116-X. PMID: 30962167Free PMC Article
State-of-the-art nanopathological diagnostics.
Roncati L, Barbolini G
Ultrastruct Pathol 2017 Sep-Oct;41(5):309-311. Epub 2017 Aug 14 doi: 10.1080/01913123.2017.1358227. PMID: 28805487
Pneumoconioses.
Karkhanis VS, Joshi JM
Indian J Chest Dis Allied Sci 2013 Jan-Mar;55(1):25-34. PMID: 23798087

Therapy

Research progress on the pathogenesis and prediction of pneumoconiosis among coal miners.
Hang W, Bu C, Cui Y, Chen K, Zhang D, Li H, Wang S
Environ Geochem Health 2024 Jul 16;46(9):319. doi: 10.1007/s10653-024-02114-z. PMID: 39012521
Distract, delay, disrupt: examples of manufactured doubt from five industries.
Goldberg RF, Vandenberg LN
Rev Environ Health 2019 Dec 18;34(4):349-363. doi: 10.1515/reveh-2019-0004. PMID: 31271562
Dust to dust.
McGuire C
Lancet Respir Med 2019 May;7(5):383-384. Epub 2019 Apr 5 doi: 10.1016/S2213-2600(19)30116-X. PMID: 30962167Free PMC Article
Coal mine dust lung disease in the modern era.
Perret JL, Plush B, Lachapelle P, Hinks TS, Walter C, Clarke P, Irving L, Brady P, Dharmage SC, Stewart A
Respirology 2017 May;22(4):662-670. Epub 2017 Mar 30 doi: 10.1111/resp.13034. PMID: 28370783
Small airways involvement in coal mine dust lung disease.
Long J, Stansbury RC, Petsonk EL
Semin Respir Crit Care Med 2015 Jun;36(3):358-65. Epub 2015 May 29 doi: 10.1055/s-0035-1549451. PMID: 26024344

Prognosis

Research progress on the pathogenesis and prediction of pneumoconiosis among coal miners.
Hang W, Bu C, Cui Y, Chen K, Zhang D, Li H, Wang S
Environ Geochem Health 2024 Jul 16;46(9):319. doi: 10.1007/s10653-024-02114-z. PMID: 39012521
Altered lymphatic structure and function in pleural anthracosis: negative role in skip N2 metastasis.
Takeda A, Ueda K, Aoki M, Nagata T, Kamimura G, Umehara T, Tokunaga T, Tabata K, Tanimoto A, Sato M
Eur J Cardiothorac Surg 2022 Aug 3;62(3) doi: 10.1093/ejcts/ezac123. PMID: 35211750
Bronchial Anthracofibrosis and Tracheobronchomalacia.
Samareh-Fekri M, Hashemi Bajgani SM, Shafahi A, Shafiepour M, Yazdani R, Ahmadpour Baghdadabad MH
Arch Iran Med 2021 Jun 1;24(6):467-472. doi: 10.34172/aim.2021.67. PMID: 34488309
Endobronchial Tuberculosis in Anthracotic Bronchitis.
Rezaeetalab F, Farrokh D
Pneumologia 2016 Jan-Mar;65(1):10-3. PMID: 27209834
Respiratory diseases caused by coal mine dust.
Laney AS, Weissman DN
J Occup Environ Med 2014 Oct;56 Suppl 10(0 10):S18-22. doi: 10.1097/JOM.0000000000000260. PMID: 25285970Free PMC Article

Clinical prediction guides

Research progress on the pathogenesis and prediction of pneumoconiosis among coal miners.
Hang W, Bu C, Cui Y, Chen K, Zhang D, Li H, Wang S
Environ Geochem Health 2024 Jul 16;46(9):319. doi: 10.1007/s10653-024-02114-z. PMID: 39012521
Altered lymphatic structure and function in pleural anthracosis: negative role in skip N2 metastasis.
Takeda A, Ueda K, Aoki M, Nagata T, Kamimura G, Umehara T, Tokunaga T, Tabata K, Tanimoto A, Sato M
Eur J Cardiothorac Surg 2022 Aug 3;62(3) doi: 10.1093/ejcts/ezac123. PMID: 35211750
Bronchial Anthracofibrosis and Tracheobronchomalacia.
Samareh-Fekri M, Hashemi Bajgani SM, Shafahi A, Shafiepour M, Yazdani R, Ahmadpour Baghdadabad MH
Arch Iran Med 2021 Jun 1;24(6):467-472. doi: 10.34172/aim.2021.67. PMID: 34488309
Coal mine dust lung disease in the modern era.
Perret JL, Plush B, Lachapelle P, Hinks TS, Walter C, Clarke P, Irving L, Brady P, Dharmage SC, Stewart A
Respirology 2017 May;22(4):662-670. Epub 2017 Mar 30 doi: 10.1111/resp.13034. PMID: 28370783
Anthracosis and anthracofibrosis.
Sigari N, Mohammadi S
Saudi Med J 2009 Aug;30(8):1063-6. PMID: 19668889

Recent systematic reviews

Genetic susceptibility in pneumoconiosis in China: a systematic review.
Chair SY, Chan JYW, Law BMH, Waye MMY, Chien WT
Int Arch Occup Environ Health 2023 Jan;96(1):45-56. Epub 2022 Jul 29 doi: 10.1007/s00420-022-01893-1. PMID: 35906431
Prevalence of coal worker's pneumoconiosis: a systematic review and meta-analysis.
Liu W, Liang R, Zhang R, Wang B, Cao S, Wang X, Ma J, Wang D, Chen W
Environ Sci Pollut Res Int 2022 Dec;29(59):88690-88698. Epub 2022 Jul 14 doi: 10.1007/s11356-022-21966-5. PMID: 35836046
Computer-Aided Diagnosis of Coal Workers' Pneumoconiosis in Chest X-ray Radiographs Using Machine Learning: A Systematic Literature Review.
Devnath L, Summons P, Luo S, Wang D, Shaukat K, Hameed IA, Aljuaid H
Int J Environ Res Public Health 2022 May 25;19(11) doi: 10.3390/ijerph19116439. PMID: 35682023Free PMC Article
A systematic review and meta-analysis on international studies of prevalence, mortality and survival due to coal mine dust lung disease.
Lu C, Dasgupta P, Cameron J, Fritschi L, Baade P
PLoS One 2021;16(8):e0255617. Epub 2021 Aug 3 doi: 10.1371/journal.pone.0255617. PMID: 34343220Free PMC Article
Frequency of tuberculosis in anthracosis of the lung: a systematic review.
Mirsadraee M, Saffari A, Sarafraz Yazdi M, Meshkat M
Arch Iran Med 2013 Nov;16(11):661-4. PMID: 24206409

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